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Ancillary Studies Information Central

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Ancillary Studies
HCHS/SOL is a unique source of a well-characterized population. The study welcomes ancillary study proposals that collect new information and/or biological samples directly from participants of the ongoing parent study, that address new research questions. Please review the information provided here if interested in submitting a study proposal. The information presented below is intended for potential investigators. Ancillary studies are subset studies of HCHS/SOL with goals beyond the original study.

If you are interested in submitting a proposal for an Ancillary Study, please contact one of our study PIs or email us at hchsadministration@unc.edu.


Submissions require a form found at Collaborating with HCHS/SOL webpages and are accepted through the website portal. A website account is required prior to submission of Ancillary Study Proposal. Your sponsoring HCHS/SOL PI should review the entire process with you.

Title Date File
HCHS/SOL Overlap between Ancillary Studies (Feb 2025) 02/20/2025 PDF icon PDF
HCHS/SOL Lab assays counts (V1, V2, V3 and some Ancillaries) 02/25/2025 PDF icon PDF
HCHS/SOL Biospecimen Repository 07/15/2024 PDF icon PDF
HCHS/SOL Ancillary Study Timeline (through 2024) 03/25/2025 PDF icon PDF
HCHS/SOL Ancillary Study Timeline (4th Visit Coordination) 12/03/2024 PDF icon PDF
HCHS/SOL Ancillary Study Implementation 02/22/2023 PDF icon PDF
Genetics-Omics Inventory Summary - May 2024 05/20/2024 PDF icon PDF
Funded Ancillary Studies Information 02/25/2025 PDF icon PDF
Ancillary Study Committee - Membership & Reviewer List 02/20/2025 PDF icon PDF
Ancillary Studies Proposing Investigator Checklist 07/12/2024 PDF icon PDF
Ancillary Studies Introduction / Overview 03/12/2025 PDF icon PDF
1. Policy (updated Feb 2025) 02/25/2025 PDF icon PDF
2. Ancillary Study Process within the HCHS/SOL Management Structure 05/24/2019 PDF icon PDF
2. Word Form - Consortium Request Submission Form 05/07/2024 File DOCX
- b. Word Form - Ancillary Study Concept Submission 03/14/2025 File DOCX
- c. Word Form - Ancillary Study Full Proposal 03/14/2025 File DOCX
- d. Word Form - Secondary Data Analyses Ancillary Study 03/14/2025 File DOCX
- e. Word Form - Approved Ancillary Study Amendment Submission 05/07/2024 File DOCX
3. NIH/NHLBI Opportunities, Policies, Guidelines for Ancillary Study Funding 04/01/2015 PDF icon PDF
4. Ancillary Studies Implementation Planning Worksheet 09/26/2016 File DOCX
Addendum - Special Notes for the PI of approved HCHS/SOL Ancillary Studies 05/24/2019 PDF icon PDF
Guidelines for Use of HCHS/SOL Data in Ancillary Study Proposals 04/11/2012 PDF icon PDF